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Superior Safety of Reboxetine Over Amitryptiline in the Elderly

M. W. Agelink, H. Ullrich, P. Passenberg, K. Sayar, N. H. Brockmeyer

Under antidepressive treatment with amitryptiline (100 mg/d) a 71-year old woman developed delirious symptoms, hyponatremia and a grand mal seizure followed by cardiovascular arrest. A few month later she ingested 48 mg reboxetine with suicidal intent.

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